
Cardiothoracic Surgery Team
Looking for a heart
clinic in Arkansas?
At the Heart Center, we have come of the
best pediatric cardiovascular surgeons available anywhere.
State-of-the-art surgical care for children
and adults with congenital heart disease, balanced
with utmost compassion and hope…this
is the pediatric cardiothoracic surgical program,
part of the Heart Center at Arkansas Children's Hospital. Although
our focus is on patients from the south central United
States, our pediatric
cardiothoracic services reach far beyond those boundaries to
a nationwide and even international level. From the tiniest of
neonates with the most complex cardiac malformations,
to continuing-care adults with conditions present since
birth, our outcomes and results are unexcelled anywhere. That's
because we have some of the best pediatric cardiovascular
surgeons available. So next time you're looking for
a heart clinic in Arkansas, choose the Heart
Center at Arkansas Children's Hospital.
At the Heart Center, we also
have some of the best pediatric cardiologists available.
The Heart Center at Arkansas Children’s Hospital. We
strive for early and complete repair of congenital heart malformations
with the latest technological advances. Our family-centered
care environment is the foundation of the personal,
human relationships with our patients and families.
The Heart Center at Arkansas Children’s Hospital. We
offer the best care possible. We offer hope.
Here’s what parents are saying about the
Heart Center at Arkansas Children’s Hospital:
“We are so happy that ACH is the hospital chosen
for our son. It will be a part of our lives & his for a long time!”
“I can truly say that the entire CVICU team is
a shining example of the great things that can be accomplished in medicine.”
“Thank you all for your caring ways! Children’s
is a wonderful hospital, and Arkansas is VERY lucky to have you.”
“To all the staff in CV, I can never thank everyone
for the outstanding care & friendship you have given me & my
family. It was great to have a staff that is professional & passionate
about their work. To me that is unique. I am blessed to have had all
of you be a part of my life. I thank you from the bottom of my new heart.”
“Thank you all in the CVICU for your kindness in our hard time.
The Chaplain was kind & considerate to us. He came practically every
day to check on us.”
“We are so grateful for all these blessed hands.”
Robert D.B. "Jake" Jaquiss, M.D. | Michiaki
Imamura, M.D., Ph.D. | William Fiser, M.D.

Robert D.B. “Jake” Jaquiss, M.D.
Position at ACH: Chief, Pediatric and Congenital Cardiothoracic
Surgery
Academic Rank at UAMS: Professor of Surgery
Other Positions: Co-Director ECMO Program
Primary Focus/Key Word: Neonatal and pediatric cardiac
surgery
Clinical Areas of Interest: Neonatal and pediatric
cardiac surgery, adult congential heart surgery, cardiac transplantation,
ECMO, ventricular assist devices
Research Interest/Projects: outcomes after pediatric
cardiac surgery
Education
Undergraduate:
Wabash College 1982, A.B., Summa Cum Laude
Medical School
Vanderbilt University School of Medicine 1986, M.D.
Post Graduate Training
Surgery Residency - Washington University
School of Medicine 1986-1990
Cardiac Surgical Research Fellowship - Washington
University School of Medicine 1990-1992
Cardiothoracic Surgery Residency – Washington
University School of Medicine 1992-1994
Pediatric Cardiothoracic Surgery Fellowship – St.
Louis Children’s Hospital 1994-1995
Board Certifications: American Board of Thoracic Surgery
1995 (recertified 2005)
Special Awards, Appointments &/or Honors: Phi Beta
Kappa, Alpha Omega Alpha
Recent most significant manuscripts, abstracts, presentations:
- Jaquiss RDB.
Coarctation of the aorta: end-to-end anastomosis.
OPER TECH THOR CARDIOVASC SURG 2002;7(1):2-10.
- Rafiee R, Shi Y, Kong X, Pritchard Jr KA, Tweddell
JS, Litwin SB, Mussatto K, Jaquiss RDB,
Su J, Baker JE. Activation of protein kinases in
chronically hypoxic infant human and rabbit hearts – role
in cardioprotection. CIRCULATION 2002;106:239-45.
- Jaquiss RDB, Ghanayem NS, Zacharisen
MZ, Mussatto KM, Tweddell JS, Litwin SB. Safety of
aprotinin use and re-use in pediatric cardiothoracic
surgery. CIRCULATION 2002;106(suppl I):I-90-I-94.
- Tweddell JS, Hoffman GH, Mussatto KM, Fedderly
RT, Berger S, Jaquiss RDB, Ghanayem
NS, Frisbee SJ, Litwin SB. Improved survival of patients
undergoing palliation of hypoplastic left heart syndrome: lessons
learned from 115 consecutive patients. CIRCULATION
2002;106(suppl I):I-82-I-89.
- Ghanayem NS, Hoffman GM, Mussatto KA, Cava JR,
Frommelt PC, Rudd NA, Steltzer MM, Bevandic SM, Frisbee
SJ, Jaquiss RDB, Litwin SB, Tweddell
JS. Home surveillance program prevents interstage
mortality after the Norwood procedure. J THORAC CARDIOVASC
SURG 2003;126:1367-77.
- Frommelt PC, Frommelt MA, Tweddell JS, Jaquiss RDB.
Prospective echo diagnosis and surgical repair of
anomalous origin of a coronary artery from the opposite
sinus with and interarterial course. J AMER COLL
CARDIOL 2003;42:148-54.
- Rafiee P, Shi Y, Pritchard Jr. KA, Ogawa H, Eis
ALW, Komorowski RA, Fitzpatrick CM, Tweddell JS,
Litwin SB, Mussatto K, Jaquiss RDB,
Baker JE. Cellular redistribution of inducible Hsp
70 protein in the human and rabbit heart in response
to the stress of chronic hypoxia. J BIOL CHEM 2003
Oct 31;278(44)43636-44.
- Hoffman GM, Stuth EA, Jaquiss RD, Vanderwal
PL, Staudt SR, Troshynski TJ, Ghanayem NS, Tweddell
JS. Changes in cerebral and somatic oxygenation during
stage 1 palliation of hypoplastic left heart syndrome
using continuous regional cerebral perfusion. J THORAC
CARDIOVASC SURG 2004 Jan;127(1):223-33.
- Hoffman GM, Tweddell JS, Ghanayem NS, Mussatto
KA, Stuth EA, Jaquiss RD, Berger
S. Alteration of the critical arteriovenous oxygen
saturation relationship by sustained afterload reduction
after the Norwood procedure. J THORAC CARDIOVASC
SURG Surg. 2004 Mar;127(3):738-45.
- Jaquiss RDB, Ghanayem NS,
Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, R.N.,
Tweddell JS. Early cavopulmonary anastomosis in very
young infants after the Norwood procedure: impact
on oxygenation, resource utilization, and mortality.
J THORAC CARDIOVASC SURG 2004 Apr;127(4):982-9.
- Ghanayem NS, Cava JR, Jaquiss RDB,
Tweddell JS. Home monitoring of infants after stage
one palliation for hypoplastic left heart syndrome.
PEDIATR CARD SURG ANN OF SEM THORAC CARDIOVASC SURG
2004;(7) 32-8.
- Zangwill SD, Trost BA, Zlotocha J, Tweddell JS, Jaquiss RDB,
Berger S. Orthotopic heart transplantation in a child
with histiocytoid cardiomyopathy. J HEART LUNG TRANSPLANT
2004;23:902-4.
- Jaquiss, RDB, Tweddell, JS, Litwin
SB. Surgical Therapy for Sudden Cardiac Death in
Children. PEDIATR CLIN NORTH AM 2004 Oct;51(5):1389-400.
- Rosenthal D, Chrisant MR, Edens E, Mahony L, Canter
C, Colan S, Dubin A, Lamour J, Ross R, Shaddy R,
Addonizio L, Beerman L, Berger S, Bernstein D, Blume
E, Boucek M, Checchia P, Dipchand A, Drummond-Webb
J, Fricker J, Friedman R, Hallowell S, Jaquiss R,
Mital S, Pahl E, Pearce B, Rhodes L, Rotondo K, Rusconi
P, Scheel J, Pal Singh T, Towbin J. International
society for heart and lung transplantation: Practice
guidelines for management of heart failure in children. J
HEART LUNG TRANSPLANT 2004 Dec;23(12):1313-33.
- Jaquiss RDB. Pediatric Tracheal
Stenosis and Tracheomalacia. SEM THORAC CARDIOVASC
SURGERY 2004 Fall;16(3):220-4.
- Tweddell JS, Pelech AN, Jaquiss RD,
Frommelt PC, Mussatto KA, Hoffman GM, Litwin SB.
Complex aortic valve repair as a durable and effective
alternative to valve replacement in children with
aortic valve disease. .J THORAC CARDIOVASC SURG 2005
Mar;129(3):551-8.
- Tweddell JS, Pelech AN, Jaquiss RD,
Frommelt PC, Mussatto KA, Hoffman GM, Litwin SB.
Aortic valve repair. PEDIATR CARD SURG ANNU OF SEM
THORAC CADIOVASC SURG 2005;112-21.
- Hoffman GH, Mussatto KA, Brosig CL, Ghanayem NG,
Musa N, Fedderly RT, Jaquiss RDG,
Tweddell JS. Systemic venous oxygen saturation after
the Norwood procedure and childhood neurodevelopmental
outcome. J THORAC CARDIOVASC SURG 2005 Oct;130(4):1094-1100.
- Jaquiss RDB, Tweddell JS. The
Neonate with Congenital Heart Disease: What
the Cardiac Surgeon Needs to Know from the Neonatologist
and the Cardiologist. CLIN PERINATOL 2005 Dec;34(4)947-962.
- Ghanayem NS, Tweddell JS, Hoffman GM, Mussatto
K, Jaquiss RD. Optimal timing of
the second stage of palliation for hypoplastic left
heart syndrome facilitated through home monitoring,
and the results of early cavopulmonary anastomosis.
CARDIOL YOUNG. 2006 Jan-Feb;16 Suppl 1:61-6.
- Zangwill SD, Ellis TM, Zlotocha J, Jaquiss RD,
Tweddell JS, Mussatto KA, Berger S. The virtual crossmatch
- A screening tool for sensitized pediatric heart
transplant recipients. Pediatr Transplant. 2006 Feb;10(1):38-4

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Michiaki Imamura, M.D., Ph.D.
Position at ACH: Cardiac surgeon, Pediatric and
Congenital Cardiothoracic Surgery
Academic Rank at UAMS (Professor, Associate Professor,
etc.): Assistant Professor
Primary Focus/Key Word: Pediatric heart surgery,
cardiac transplantation
Clinical Areas of Interest: Pediatric and congenital
heart surgery, cardiac transplantation
Research Interest/Projects: Pediatric heart surgery,
cardiac transplantation, mechanical circulatory support, ischemia reperfusion
Education
Undergraduate/Graduate: Hokkaido
University Graduate School of Medicine, Japan, 1992,
Ph.D.
Medical School: Hokkaido University
School of Medicine, Japan, 1988, M.D.
Post Graduate Training
Residency: Hokkaido University School of
Medicine, Japan, completed 1993
Fellowship:
Cornell Univ. Medical College, New York, 1993-95
Hokkaido University School of Medicine, Japan, 1995-96
The Cleveland Clinic Foundation, Ohio, 1996-99
Board Certifications:
ECFMG, 1995; USMLE 2002
Board of General Surgery of Japanese Society of Surgery,
1992
Board of Japanese Association for Thoracic Surgery,
1999
Recent (last 5 years) most significant manuscripts:
Oka J, Imamura M, Hatta E, Maruyama R, Isaka M, Murashita
T, Yasyda K. Carrier-Mediated Norepinephrine Release and Reperfusion
Arrhythmias Induced by Protracted Ischemia in Isolated Perfused Guinea
Pig Hearts: Effect of Presynaptic Modulation by alpha 2 -Adrenoceptor
in Mild Hypothermic Ischemia. J Pharma Exp Ther 2002;
303:681-687.
Imamura M, Schmitz ML, Watkins B, ChipmanCW, Faulkner
SC, Fiser WP, Jr, Van Devanter SH, Drummond-Webb JJ. Venovenous
Extracorporeal Membrane Oxygenation for Cyanotic Congenital Heart Disease. Ann
Thorac Surg 2004; 78: 1723-1727.
Imamura M, Hale S, Johnson CE, Schmitz ML, Morrow WR,
Fiser WP, Drummond-Webb JJ. The First Successful DeBakey VAD Child Implantation
as a Bridge to Transplantation. ASAIO Journal 2005;
78: 1723-1727.
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William Fiser, M.D.
Position at ACH: Research Director, Pediatric and Congenital
Cardiothoracic Surgery
Academic Rank at UAMS (Professor, Associate Professor etc.): Assistant
Professor of Surgery
Other Positions: Medical Director, Arkansas Regional
Recovery Agency (ARORA)
Primary Focus/Key Word: cardiac transplant / ECMO/ mechanical
support
Clinical Areas of Interest: ECMO, mechanical cardiac
support
Research Interest/Projects: Cardiac
surgery outcomes, ECMO outcomes, Mobile ECMO, Berlin Heart, DeBakey VAD
child & various clinical investigations in cardiac surgical patients
Education
Undergraduate/Graduate:
Hendrix College
Conway, AR
Harvard University, 1973
Cambridge, Massachusetts
Medical School:
University of Arkansas for Medical Sciences
1975-1979 - M.D.
Post Graduate Training:
Residency:
University of Arkansas for Medical Sciences
1980-1984, General Surgery Residency
Fellowship:
University of Arkansas for Medical Sciences
1985-1986, Thoracic Surgery Residency
Board Certifications: American Board of
Surgery, American Board of Thoracic Surgery
Recent (last 5 years) most significant manuscripts:
- Imamura M. Hale S. Johnson CE. Schmitz ML. Morrow
WR. Fiser WP. Drummond-Webb JJ.
The first successful DeBakey VAD child implantation
as a bridge to transplant. [Case Reports. Journal
Article] ASAIO Journal. 51(5):670-2, 2005 Sep-Oct.
Imamura M. Schmitz ML. Watkins B. Chipman CW. Faulkner
SC. Fiser WP Jr. Van Devanter SH.
Drummond-Webb JJ. Venovenous extracorporeal membrane
oxygenation for cyanotic congenital heart disease.
[Review] [9 refs] [Evaluation Studies. Journal Article.
Review] Annals of Thoracic Surgery. 78(5):1723-7,
2004 Nov.
UI: 15511462
- Eble BK. Fiser WP. Simpson P.
Dugan J. Drummond-Webb JJ. Yetman AT. Mitral valve
replacement in children: predictors of long-term
outcome. [Journal Article] Annals of Thoracic Surgery.
76(3):853-9; discussion 859-60, 2003 Sep.
- Fiser WP. Yetman AT. Gunselman
RJ. Fasules JW. Baker LL. Chipman CW. Morrow WR.
Frazier EA. Drummond-Webb JJ. Pediatric arteriovenous
extracorporeal membrane oxygenation (ECMO) as a bridge
to cardiac transplantation. [Evaluation Studies.
Journal Article] Journal of Heart & Lung Transplantation.
22(7):770-7, 2003 Jul.
- Yetman AT. Drummond-Webb J. Fiser WP.
Schmitz ML. Imamura M. Ullah S. Gunselman RJ. Chipman
CW. Johnson CE. Van Devanter SH. The extracardiac
Fontan procedure without cardiopulmonary bypass:
technique and intermediate-term results. [Journal
Article] Annals of Thoracic Surgery. 74(4):S1416-21,
2002 Oct.
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